Currently Available Rescue Dogs

NEW RESEARCH COLLABORATION

EXOCRINE PANCREATIC INSUFFICIENCY (EPI)

CANCER GENETICS AND COMPARATIVE GENOMICS BRANCH
NATIONAL HUMAN GENOME RESEARCH INSTITUTE
NATIONAL INSTITUTES OF HEALTH


As leaders of the Dog Genome Project at the National Human Genome Research Institute(NHGRI) of the National Institutes of Health (NIH), we are writing to discuss a possible new collaboration with your breed club.  Our laboratory has a long standing goal of dissecting the role of genomic changes controlling both simple and complex diseases, specifically in the realm of disease susceptibility.

We have recently initiated a new project aimed at identifying the genetic components that increase pancreatic inflammation in purebred dogs, with a particular focus on exocrine pancreatic insufficiency (EPI).  As you probably know, EPI is closely related to pancreatitis as it is characterized by insufficient synthesis of digestive enzymes.  While EPI may occur secondarily to repeated pancreatic inflammation, there is substantial evidence for a heritable, breed-specific risk component of the disease.  We aim to identify genetic variants that predispose certain breeds to EPI as a first step in better understanding other more complex pancreatic disorders in dogs.

We are contacting your breed club because of the established risk for this disorder among English Cocker Spaniels.  We are asking for your help in contacting members of the English Cocker community who have had dogs diagnosed with EPI or other pancreatic conditions who are willing to provide DNA samples.  We also need DNA samples of healthy English Cockers, who must be 10 years of age or older.  We will provide DNA collection kits to any owner that elects to participate.  Kits include a one page consent form, materials for collecting blood at their primary veterinarian’s office, and instructions for returning the collected sample.  The kit is provided in a mailer tube approved for shipping biological materials by the U.S. Postal Service.  Samples submitted from dogs with pancreatic disorders should also include a copy of relevant veterinary diagnostic results.  Any diagnostic method will be useful, although “SNAP” test of enzyme activity and blood chemistry are ideal.  Cytology and histopathology can also be accepted.  Pedigree information is also great appreciated, if available.  Participation in the study and any information provided to us will remain strictly confidential and samples are only identified by coded numbers.

Our laboratory has had many productive relationships with breed clubs like yours that have resulted in the identification of genes for various types of cancer, retinal disease, and other disorders.  All of this work is based on our successful published efforts to both build tools and analyze sequence analysis from the canine genome.  In the last 25 yrs, our research has proven critical for improving the health of purebred dogs.

Sincerely,
Elaine A. Ostrander, Ph.D.
Chief and Distinguished Investigator
Cancer Genetics and Comparative Genomics Branch
National Human Genome Research Institute
National Institutes of Health

*Edited for republication


Contact:

Andrew Hogan [C] Samples Manager
Dog Genome Project, NIH/NHGRI
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Office: (301) 451-9390 Fax: (301) 594-0023
Bldg.50, Room 5347
50 South Drive, Bethesda, MD 20892

Dr. Dayna Dreger, Project lead scientist, will answer questions related to the study. This email address is being protected from spambots. You need JavaScript enabled to view it.

If you’d like to learn more about the Dog Genome Project and their work visit their website: http://research.nhgri.nih.gov/dog_genome

THIS RESEARCH IS OPEN TO ENGLISH COCKERS WORLDWIDE

Research on Canine Inflammatory Bowel Disease (IBD) is ongoing at Texas A&M University. This study is for all breeds. 

http://vetmed.tamu.edu/gilab/research/canine-ibd

The ECSCA Health Organization
is sponsoring research for
Addison’s Disease & Immune-Mediated Hemolytic Anemia (IMHA)

We need the participation of affected English Cockers!

If you have an AFFECTED DOG with either disease or know someone that has an AFFECTED DOG PLEASE visit the special website for additional information. Participation is easy and it only requires your time to take the dog to your attending DVM.  We need a blood sample from the affected dog. OUR RESEARCH will pay for shipping the sample and Dr. Friedenberg will call your attending DVM with details prior to your appointment. Attending DVMs generally donate their time for this special collection. WE CAN NOT MOVE FORWARD WITH THIS PROJECT UNTIL WE HAVE A MEANINGFUL NUMBER OF PARTICIPANTS IN THE STUDY! We are anxious to move forward with the next steps!

If you have a dog that has recovered from IMHA, you may be eligible to participate if you have records confirming the diagnosis.

PLEASE CONTACT

Steven G. Friedenberg, DVM, PhD, DACVVECC
Assistant Professor, Department of Veterinary Clinical Sciences
University of Minnesota College of Veterinary Medicine
1352 Boyd Avenue
339 VetMedCtrS
Saint Paul, MN 55108
612-624-5148

This email address is being protected from spambots. You need JavaScript enabled to view it.

Addision's Disease Information

IMHA Information

DNA SAMPLES FOR COCKER SPANIEL ITP STUDY

What is ITP?

Immune thrombocytopenia (ITP also known as IMT) causes spontaneous bleeding and bruising because the body destroys its own normal blood platelets. This is an autoimmune disease that typically develops in adult dogs. Although Cocker Spaniels have an increased risk for ITP, the environmental and genetic causes remain unknown. Our goal is to identify immune and genetic factors that cause ITP so that we can improve disease diagnosis and treatment. Your dog’s blood samples will help us accomplish these goals. Thank you for your support!

For questions, please contact: Dr. Dana LeVine This email address is being protected from spambots. You need JavaScript enabled to view it. or Dr. Marjory Brooks This email address is being protected from spambots. You need JavaScript enabled to view it.
                            
Marjory Brooks, DVM, DACVIM            
Animal Health Diagnostic Laboratory            
Cornell University
                    
Dana LeVine, DVM, DACVIM, PhD
Veterinary Clinical Sciences
Iowa State University

Download Sample Form Here

The ECSCA Health Organization
is sponsoring research for
Addison’s Disease & Immune-Mediated Hemolytic Anemia (IMHA)

We need the participation of affected English Cockers!

If you have an AFFECTED DOG with either disease or know someone that has an AFFECTED DOG PLEASE visit the special website for additional information. Participation is easy and it only requires your time to take the dog to your attending DVM.  We need a blood sample from the affected dog. OUR RESEARCH will pay for shipping the sample and Dr. Friedenberg will call your attending DVM with details prior to your appointment. Attending DVMs generally donate their time for this special collection. WE CAN NOT MOVE FORWARD WITH THIS PROJECT UNTIL WE HAVE A MEANINGFUL NUMBER OF PARTICIPANTS IN THE STUDY! We are anxious to move forward with the next steps!

If you have a dog that has recovered from IMHA, you may be eligible to participate if you have records confirming the diagnosis.

PLEASE CONTACT

Steven G. Friedenberg, DVM, PhD, DACVVECC
Assistant Professor, Department of Veterinary Clinical Sciences
University of Minnesota College of Veterinary Medicine
1352 Boyd Avenue
339 VetMedCtrS
Saint Paul, MN 55108
612-624-5148

This email address is being protected from spambots. You need JavaScript enabled to view it.

Addision's Disease Information

IMHA Information

Copyright 2011. Joomla 1.7 templates.