Addison's Disease

The ECSCA Health and Rescue Organization is pleased to support and officially launch our next BIG research projects: Immune Mediated Hemolytic Anemia (IMHA/AIHA) and Addison’s Disease. Dr. Steven Friedenberg, North Carolina State University, will lead the studies on both of these devastating diseases. This project will be far more complicated than our past three successful endeavors: prcd, FN, and AN.

The blood sample submissions are just the beginning. We will need 50 control dogs (dogs free from both diseases and over age 10), 50 dogs affected with IMHA, and 50 dogs affected with Addison’s Disease.
Once we have 150 informative dogs sequence work will begin. The ECSCA will then seek outside funding. As the end of the year approaches please remember to support this research with a donation. We are now a 501-c3 charitable tax organization. We truly appreciate your support, past and present and we hope to one day soon add two more DNA tests to the tool box!

Information on participation on both diseases can be found on newly created web sites. We are fortunate to have Dr. Friedenberg’s dedication and expertise in this endeavor.

Please contact him if you have a dog that you’d like to participate in either study.

If you have any questions about the study please contact someone on the Health Committee.

With Great Enthusiasm,
Addi Pittman, Chairman
Genelle Joseph
Elizabeth Neff
Joyce Winkels
Bruce Barrett, DVM

Addison's Disease

Dr. Steven Friedenberg at North Carolina State University and the English Cocker Spaniel Health and Rescue Organization have officially started collecting blood samples from English Cocker Spaniels who have Addison's disease, and from older dogs (>10y) who do not have Addison's disease. We're very excited to get going with this endeavor as we hope that someday it will help us find the genes that cause this disease. This study will piggyback on Dr. Friedenberg's work on Addison's disease in other breeds. All that's required to participate is a small blood sample, and the study pays for all of the associated costs. For more info, check out our study web site at http://www.ncstatevets.org/english-cocker-spaniels-addisons-disease/ or reach out to Dr. Friedenberg at This email address is being protected from spambots. You need JavaScript enabled to view it. for more info.

 

Research Update ~ November 2015

I just received our first update on our newest research project for Addison’s Disease and AIHA under the guidance of Dr. Steven Friedenberg, North Carolina State University. We launched this research about six weeks ago. 

We sincerely THANK our participants for submitting blood samples and truly appreciate your interest and help. 

We’ve fallen short of our anticipated goal and we need many more participants. If you own a dog affected with Addison’s or AIHA/IMHA PLEASE contact Dr. Friedenberg for details regarding your participation. Links are shown below. 

We MUST have 50 AFFECTED DOGS for each study. If you own a Cocker in remission that was diagnosed with AIHA/IMHA you can participate!  If you take a dog to the ER and you suspect AIHA/IMHA PLEASE ask the attending doctor to draw extra blood BEFORE drugs are given. We do need blood samples for RNA studies, but most facilities will not have the special test tubes that are needed for this study, but the blood can still be used in the study. A simple purple-top EDTA test tube is all that is needed.  AIHA/IMHA is an emergency situation and the main concern is the dogs life and that involves immediate attention. Try to remember to ask for extra blood when they are testing to confirm this disease.  Put it in the refrigerator  and contact Dr. Friedenberg for a shipping label. 

Please visit the websites for details on these two very important research studies! We NEED YOUR SUPPORT.  Should you have any questions about the research don’t hesitate to contact me or anyone on the Health Committee.

The year is nearly over…Please remember the ECSCA Health Research Projects depend on your contributions!  We are funding both these research projects. We are a 501-c3 tax deduction. Our website takes credit cards and PayPal.

Please help us to help you and most importantly our cockers!  

http://www.ncstatevets.org/english-cocker-spaniels-addisons-disease/
http://www.ncstatevets.org/english-cocker-spaniels-imha/
http://ecscahealthandrescue.org/

Current Statistics

15 control/normal dogs are enrolled       35 MORE ARE NEEDED!!!
2 dogs with Addison’s Disease are enrolled   48 MORE ARE NEEDED!!!
9 dogs were sent in as controls, but their baseline cortisols were less than 2—which means their results at this time are equivocal/uncertain.  Hopefully owners of these dogs will retest and let Dr. Friedenberg know if/when their status changes.  These samples will be kept for research purposes.

1 dog with AIHA was enrolled.  49 MORE ARE NEEDED!!!

As you can see, we have a long way to go to reach the numbers we need:  50- Control Dogs that are CLEAR for both Addison’s & AIHA/IMHA These dogs should be a minimum of 10 years old. 50- AFFECTED with Addison’s Disease    50-AFFECTED with AIHA/IMHA

Addi Pittman, Chairman
ECSCA Health Education
Genelle Joseph
Elizabeth Neff
Joyce Winkels
Bruce Barrett, DVM

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